Immunohistochemistry Kits and Reagents
BIOHIPPO Phospho- Ser/Thr PDK1 Docking
U-Blot Phospho-(Ser/Thr) PDK1 Docking Motif Mouse mAb is a Mouse-derived recombinant monoclonal antibody (clone W-R31) that specifically recognizes Phospho-(Ser/Thr) PDK1 Docking Motif a phosphorylation modification at Serine/Threonine residues in the PDK1 docking motif It shows reactivity with Human Validated applications include WB Recommended dilutions WB 1500-11000 Purified by protein a Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine in a hydrophobic motif For example Akt a kinase that regulates cell survival is activated by phosphorylation at Ser473 a site preceded by Phe at -4 and -1 and followed by Tyr at 1 RSK2 p70 S6 kinase and certain PKC isoforms also contain a similar consensus phosphorylation motif Phosphorylation of these motifs is required for binding to 3-phosphoinositide dependent kinase 1 (PDK1) Supplied as 100 uL
Meridian Life Science Lyo-Ready Direct RNA/DNA, 5ML
Lyo-Ready RNA/DNA LAMP Stool mix combines even greater tolerance with fast, robust isothermal amplification to enable highly sensitive direct detection using crudely processed stool samples. The mix is uniquely designed to overcome much higher concentrations of inhibitors, and so do not require a DNA or RNA purification step to concentrate and purify a patient sample. Very fast reaction kinetics result in faster time to results and superior amplification sensitivity and specificity. In addition, the 4x concentrated master mix is formulated with lyo-excipients which are optimized for freeze-drying to create ambient-temperature stable assays, making it ideal for POC stool testing.
ACROBiosystems Biotinylated Human Nectin-4 (154-243) Protein, His, Avi tag (NE4-H82Ec)
Recombinant biotinylated extracellular fragment of human Nectin-4 (Asn 154-Ser 243) expressed in HEK293 cells. The protein includes an N-terminal polyhistidine tag and an Avi tag for site-specific enzymatic biotinylation, and is supplied as a glycosylated protein suitable for binding and detection assays.
- Expressed in HEK293 cells for mammalian glycosylation.
- Contains amino acids Asn 154-Ser 243 of human Nectin-4.
- N-terminal polyhistidine and Avi tag for purification and site-specific biotinylation.
- Enzymatically biotinylated at the Avi tag for streptavidin-based capture or detection.
- Glycosylated; apparent molecular weight 15-30 kDa on SDS-PAGE.
- Purity >90% by SDS-PAGE.
- Suitable for binding assays, ELISA, SPR, and receptor interaction studies.
Meso Scale Discovery R-PLEX Human FABP3/H-FABP ASY
The R-PLEX Human FABP3 (H-FABP) Assay Kit from Meso Scale Discovery is a multiplex immunoassay that quantitatively measures human Heart-type Fatty Acid Binding Protein (H-FABP) in serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to a 7-log dynamic range and low sample volume requirements The kit includes a 96-well plate pre-coated with capture antibody detection antibody Read Buffer Sample Diluent and Calibrator This assay can detect H-FABP levels as low as 19 pg/mL with an approximate 3 5 hour total assay time
Meso Scale Discovery R-PLEX Human ACE2 ASYQP
The R-PLEX Human ACE2 Assay from Meso Scale Discovery measures human ACE2 levels in serum plasma and cell culture supernatants using MSD s electrochemiluminescence technology It offers high sensitivity a dynamic range of up to 5 logs and low sample volume requirements The assay quantifies ACE2 levels from 0 05 to 10 000 pg/mL with high specificity and minimal cross-reactivity Available as a singleplex assay it includes a plate with capture antibody detection antibody and calibrator aiding in the study of ACE2 levels related to COVID-19 infection and progression
Medchemexpress LLC Plasmalemma vesicle-associated protein (PLVAP), human recombinant (HEK293, His tag) | ≥95.0% | 100UG
Recombinant human plasmalemma vesicle-associated protein (PLVAP) is supplied as a lyophilized, HEK293-expressed His-tagged protein for research on endothelial barrier function and microvascular permeability. The material is provided with low endotoxin and guidance for reconstitution and storage to support biochemical and cell-based studies.
- Species: human.
- Source: HEK293 expression system.
- Tag: His tag for purification.
- Purity: ≥95.0% as determined by Tris-Bis PAGE.
- Molecular weight: 50-70 kDa.
- Formulation: lyophilized from PBS with 200 mM l-arginine and 8% trehalose.
- Endotoxin: <1 EU/μg.
- Storage: store lyophilized at -20°C; aliquot and freeze after reconstitution.
ABclonal Technology KO Validated Claudin 1
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome
American Research Products Inc Mouse Protein CYR61 CYR61 EL
Mouse Protein CYR61 (CYR61) ELISA kit from CUSABIO Detection Range 18 75 pg/mL-1200 pg/mL Sensitivity 4 68 pg/mL Sample serum plasma tissue homogenates Method Sandwich
Biocare Medical, LLC Background Terminator - 100 ml
Background Terminator is the ultimate blocking reagent for many sources of nonspecific background staining in immunohistochemical techniques. Studies have shown it is superior to goat serum, dried milk, gelatin and BSA blocking reagents.
ABclonal Technology S100P Rabbit pAb
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.
Meridian Life Science Lyo-Ready Direct RNA/DNA, 50ML
Lyo-Ready RNA/DNA LAMP Saliva mix combines even greater tolerance with fast, robust isothermal amplification to enable highly sensitive direct detection using crudely processed saliva or sputum samples. The mix is uniquely designed to overcome much higher concentrations of inhibitors, and so do not require a DNA or RNA purification step to concentrate and purify a patient sample. Very fast reaction kinetics result in faster time to results and superior amplification sensitivity and specificity. In addition, the 4x concentrated master mix is formulated with lyo-excipients which are optimized for freeze-drying to create ambient-temperature stable assays, making it ideal for POC saliva testing.
MOLECULAR DEPOT LLC Beta-2 Microglobulin Ab -50 mg
Human Beta-2 Microglobulin Antibody is a Goat polyclonal antibody specific to human Beta-2 microglobulin This IgG fraction purified antibody has been tested in several immunoassays For in vitro research use only